The New Chemistry Building

Chemistry and Biochemistry Building.

The Department of Chemistry and Biochemistry at Montana State University understands the important roll of instrumentation in research and training. Our department is committed to providing students, faculty, and staff with the instruments they require to stay at the forefront of research.

Structural Biology is well represented in our department and both NMR and X-ray equipment are available. Chemists and Biochemists alike benefit from the excellent NMR Instrumentation; 600, 500, 300, and 250 MHz NMR spectrometers. These instruments are used in routine analysis of small molecules and also protein structural determination.

The center for X-ray crystallography has a macromolecular X-ray program.

Computational chemistry is being served by a 64 processor Linux cluster with Intel 32-bit and 64-bit processors organized into 14 nodes. These nodes are equipped with the latest versions of a broad spectrum of molecular modeling and electronic structure calculation software, such as Gaussian, Jaguar, Amsterdam Density Functional, MOPAC2000, MacroModel, and Tinker. Intel and Portland Group compilers are available for software development.

The Department also boasts high frequency CW and pulsed EPR instrumentation, a dynamic light scattering instrument, an isothermal titration microcalorimeter, an ultrafast femtosecond laser system, 3 tunable high resolution Nd: YAG pumped pulsed dye laser systems, and a quartz crystal microbalance capable of monitoring dissipation. Investigations of high energy gas-phase and gas-surface molecular interaction are conducted using a molecular beam apparatus that was originally designed by Nobel Laureate, Y. T. Lee, for crossed-beam studies of elementary reaction dynamics, and is one of the premier machines in the world for this purpose. Employing a pulsed hyperthermal atomic-oxygen beam, produced by laser detonation of O2, a wide range of high energy reaction are conducted with this apparatus. We have spectrometers for Raman, FTIR, fluorescence, CD/MCD, and X-ray photoelectron spectrometry. In addition the equipment housed in our department, campus microscopy capabilities include transmission electron microscopy (TEM), scanning electron microscopy with cryogenics (SEM), atomic force microscopy (AFM), confocal imaging, and laser micro dissection and capture.

The mission of the Mass Spectrometry, Proteomics, and Metabolomics Facility is to seed methods, technology, and applications to research labs at Montana State University and affiliated programs. This facility offers a full range of services from single samples to complete shotgun proteomics and metabolomics projects.

Periodic hands-on training sessions are offered by the Facility. The goal of the training modules is to expand facility access to researchers with little previous training in proteomics, metabolomics, or mass spectrometry. Individual training can also be arranged. Please contact the facility personnel listed below if you wish to be trained. The Mass Spectrometry and Proteomics Facility is supported with funding from the CoBRE Center for the Analysis of Cellular Mechanisms and Systems Biology and the Murdock Charitable Trust.

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