Department of Chemistry and Biochemistry-Spring 2017

Unless noted otherwise, All Friday Seminars will begin at 3:10 pm and take place in the Byker Auditorium-Chemistry Biochemistry Building.

January 2017

Friday, January 13

Dr. James Crawford (Genetech) will present "Discovery of GDC-0853: A Highly Potent, Selective, and Non-Covalent Btk Inhibitor." Byker Auditorium at 3:10. Professor Matt Cook will host.

Friday, January 27

Garrett Moraksi, Research Scientist in the Department of Chemistry and Biochemistry (MSU) will present "To Be or Not To Be—That is the Congestion Discovery and Development of ND-10885 as an Anti-Tuberculosis Treatment."  Byker Auditorium at 3:10 pm

February

Friday, February 3

Dr. Tim Kowalczyk, Assistant Professor in the Department of Chemistry, Advanced Materials Science and Engineering Center, and Institute for Energy Studies at Western Washington University will present "Photoactive Organic Materials Design".  Byker Auditorium at 3:10 pm.  Professor Robert Szilagyi will host.

Friday, February 10

Dr. Daniel Raftery from the University of Washington will present "New Methods in Metabolomics and Applications to Colon Cancer."  Byker today at 3:10 pm Professor Valerie Copie will host. 

Friday, February 17

Dr. Xi Chu from the University of Montana, Department of Chemistry, will present “DFT and TDDFT for transition metal atoms, complexes, and more.”  Today at 3:10 pm in the Byker Auditorium.  Professor Erik Grumstrup will be the host for Dr. Chu.

Friday, February 24

Assistant Professor Matt Queen (MSU Billings)

March

Friday, March 10

Kopriva Graduate Student Seminar- Arianna Celis-Luna

Friday, March 17- Spring break

Tuesday March 21

Dr. John Kiely  4 - 4:30 pizza reception

 4:30 Seminar: Basic Quinolone Chemistry and Biology, and What to Expect as You're Entering a Career in Science

Wednesday March 22

Mr. Sam Bernhard will present his 4th Year Graduate Student Seminar titled "Exploring Glycopolymer Mediated Protein Nucleation." Byker Auditorium at 3 pm.  Sam works in the laboratory of Professor Mary Cloninger. 

Friday, March 24-

Professor Dipannita Kalyani from the Chemistry Department at St. Olaf College will present "Synthesis and Derivatization of Heterocycles Using Palladium or Nickel Catalysis." Byker Auditorium at 3:10.  Dr. Kalyani is the guest of Professor Sharon Neufeldt.

Friday, March 31

Emily Weinert (Emory University).  Professor Jen DuBois

April

Friday, April 7-OPEN

Wednesday, April 12 Ph.D Defense in Chemistry

Ms. Amanda Mattson will defend her Ph.D. beginning with a seminar titled "The Synthesis and Study of TF Antigen Functionalized Dendrimers". 1 pm in the Byker Auditorium.  Amanda works in the lab of Professor Mary Cloninger.

Friday, April 14 Ph.D Defenses in Chemistry

Ms. Christine Gobrogge will defend her Ph.D in Chemistry beginning with a seminar titled "Temperature Dependent Solvation in Phospholipid Membranes."  9 am in the Byker Auditorium.  Christine works in the lab of Professor Rob Walker.

Ms. Rebecca Danforth will defend her Ph.D in Chemistry beginning with a seminar titled "Ultrafast Photochemistry of Aqueous Iron (III) Complexes".  2 pm in the Byker Auditorium.  Rebecca is co-advised by Professors' Bern Kohler and Erik Grumstrup.

Monday April 17th

Colin Miller will present "Redox Signaling in Thioredoxin Reductase-1 and Glutathione Reductase Null Mouse Livers" for his 4th Year Graduate Student Seminar in the Department of Chemistry and Biochemistry.  Byker Auditorium at 2 pm.  Colin is co-advised by Professor Mary Cloninger and Professor Ed Schmidt.

Friday, April 21 

Dr. Larry Overman, Distinguished Professor of Chemistry, University of California-Irvine is the College of Letters and Science Distinguished Lecturer and a guest of Professor Mary Cloninger.  Dr. Overman will present "Fragment Coupling and Constructing Quaternary-Carbon Stereocenters Using Carbon Radicals." Abstract

Thursday April 27th

Ms. Natasha Pence will present a 3rd year graduate student seminar titled "Defining interactions between flavodoxin and the nitrogenase Fe protein provide mechanistic insight into the Fe protein cycle."  11 am in the Byker Auditorium.  

Friday, April 28

The Departments of Microbiology and Chemistry and Biochemistry will host Vadim Gladyshev (MIT)- Procrastinator 3:10 pm

MAY

TBD

Ms. Ashley Beckstead will defend her Ph.D in Chemistry beginning with a seminar titled "Excited-State Dynamics of Biological Molecules in Solution: Photoinduced Charge Transfer in Oxidatively Damaged DNA and Deactivation of Violacein in Viscous Solvents." 9 am Byker Auditorium.  Ms. Beckstead is co-advised by Professor Rob Walker and Professor Bern Kohler.

Department of Chemistry and Biochemistry-Fall 2017

Friday September 1

Dr. Leslie Murray - Professor Jen DuBois host

Friday September 8

Brian Hoffman - Professor Joan Broderick host

Friday September 15

Dr. Ron Shen - Graduate Student Association host

Friday September 22

Dr. Gerrick Lindberg - Professor Sharon Neufeldt host

Friday September 29

 Catherine Murphy - Professor Tim Minton host

Friday, October 6

John Kozarich of ActivX Biosciences, Joan Broderick host

Friday October, 13

Ed Rosenburg (UM) Robert Szilagyi host

Friday October 20 

Dr. George Stanley from Louisiana State University will present "Bimetallic Cooperativity in Catalysis: Twice the Fun!" 3:10 pm in the Byler. Professor Sharon Neufeldt is the host. 

Abstract:  Homobimetallic rhodium complexes using the binucleating tetraphosphine ligand racemic-(Et2PCH2CH2)(Ph)PCH2P(Ph)(CH2CH2PEt2), et,ph-P4, are highly active and selective hydroformylation catalysts for a variety of 1-alkenes.  We have investigated the nature of the bimetallic cooperativity in this novel catalyst via extensive in situ FT-IR, NMR, kinetic, isotopic labeling experiments, and DFT computational studies, all of which indicate that the key bimetallic catalyst in acetone is a unique dicationic Rh(+2) oxidation state complex, [rac-Rh2(m-H)2(CO)2(et,ph-P4)]2+.  Unfortunately, the NMR studies clearly indicate that this catalyst system is very susceptible to deactivating fragmentation reactions. 

When a 30% water/acetone solvent system is used for hydroformylation deprotonation of the dicationic dihydride species occurs generating a less active, but far more fragmentation resistant bimetallic catalyst proposed to be [Rh2(m-H)(CO)2(et,ph-P4)]+, which out-preforms the dicationic catalyst.  Based on the fragmentation problem a new, far more strongly coordinating P4 ligand that uses 1,2-phenylene based chelating groups has been designed, synthesized, and characterized.  Studies on bimetallic complexes based on this new P4 ligand will be discussed.

Friday October 27

Regan Thompson (Northwestern) Matt Cook host

Friday November 3

Dr. Steve Patterson (University of Minnesota), Garrett Moraski host

Friday Dec 1

Scott Shaw (Iowa State) Rob Walker host