Biophysics of proteins
Office: Room 55
Lab: Room 46
Chemistry and Biochemistry Building
P.O. Box 173400
Bozeman, MT 59717
Phone: 406 994 5414
Fax: 406 994 5407
- B.S. Oregon State University, Corvallis, Oregon
- Ph.D. in Physical Chemistry, University of Washington, 1965
- N.I.H. Postdoctoral Fellow, Cal Tech, 1966-68
- CHMY 361 ELEMENTS OF PHYSICAL CHEMISTRY
- CHMY 374 Physical Chemistry Lab II
- CHMY 564 ADVANCED QUANTUM CHEMISTRY
Awards and Professional Activities
- Wiley Award for Meritorious Research, 1990
- Cox Award for Teaching and Scholarship, 1992
- Phi Kappa Phi Anna Krueger Fridley Award for Distinguished Teaching, 1994
Callis Group Overview
Enzymes enormously accelerate the rates of chemical reactions over the rates of the
same reactions in water (by 108-1015 fold), but the precise manner by which enzymes accomplish this in detail is still
considered an open question.
We are making a seamless transition from obtaining a detailed understanding of how the intense internal electric fields in proteins profoundly affect the properties of tryptophan fluorescence, towards a better understanding and more detailed view of how enzymes attain their astronomical acceleration of biochemical reactions.
We are currently performing classical and quantum molecular dynamics computations on the active sites of many enzymes, with the goal of observing unbiased enzymatic reaction events.