Biochemistry
· Using dendrimers to study multivalent protein-carbohydrate interactions.
· Design of small-molecule CXCR4 antagonists for HIV and cancer treatment:
· Development of broad-spectrum antibacterial compounds:
· Nitrogenase and Nitrogen Reduction
· Novel Enzymeatic Carboxylation
· Lawrence Group Overview
· Using dendrimers to study cancer metastasis.
· Using dendrimers to study multivalent protein-carbohydrate interactions.
· Structures, Mechanisms and Biogenesis of Amine Oxidases · Novel Mechanisms for DNA Damage and Repair
· Bioremediation of Chlorinated Organics and Heavy Metals by Desulfitobacterium
· Iron Transport and Iron Homeostasis
· Archaeal Viruses and Virus-Host Interactions · Hydrogenase and Reversible Hydrogen Oxidation
· Overview · Structural Biology · NMR metabolomics · Natural Supramolecular Architectures:
Virus Capsids for Biomimetic and Bio-inspired Materials Chemistry
· Constrained Polymer synthesis, using the P22 capsid as a template · Development of in vivo targeted MRI contrast agents · Enzyme (and other gene product) Encapsulated Nanoreactors · Stress Response in an Extremophile · Systems Biology · Protein Cages as Nanomaterials · Metabolomics · Protein Dynamics |